Genome Therapeutics Corp.
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In 1961 Orrie M. Friedman [1] founded one of the first biotech companies under the name Collaborative Research Inc. (NASDAQ: CRIC) It produced one of the first linkage maps of the whole human genome in the mid 1980s.[2]
It changed its name to Genome Therapeutics (also call GTC, Genomecorp.com, NASDAQ: GENE) and produced in 1994 the first commercial genome sequence,[2] that of Helicobacter pylori, the pathogen responsible for peptic ulcers. The rights to the genome were sold to Astra AB of Sweden for $22 million and a similar deal struck with Schering-Plough.[2] In addition to infectious agents, it also worked on heritable diseases including asthma [3]
In 2004 Genome Therapeutics changed its name to Oscient Pharmaceuticals (NASDAQ: OSCIQ) [4] and its sequencing division joined with Agencourt. The latter spun out Agencourt Personal Genomics which was acquired by ABI for $120 million in 2007.[5]